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[Nutritional support in sepsis].

C Ortiz Leyba1, J López Martínez, A L Blesa Malpica

  • 1Hospital Universitario Virgen del Rocío. Sevilla.

Nutricion Hospitalaria
|June 29, 2005
PubMed
Summary
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Nutritional support for septic patients is recommended, but evidence for improved survival is limited. Enteral nutrition is preferred, with specific guidelines for caloric, protein, and micronutrient intake.

Area of Science:

  • Critical Care Medicine
  • Nutritional Science

Context:

  • Sepsis management guidelines recommend metabolic and nutritional support.
  • Evidence directly linking nutritional support to improved sepsis survival or reduced complications is scarce.
  • Current recommendations often extrapolate from data on other critically ill patient populations.

Purpose:

  • To review the current understanding and recommendations for metabolic and nutritional support in septic patients.
  • To highlight the limited specific data available for this patient group.
  • To provide guidance on enteral nutrition, caloric, and macronutrient/micronutrient administration in sepsis.

Summary:

  • Enteral nutrition is the preferred route for septic patients.
  • Caloric intake should be adjusted using a factor of 1.25-1.30 with the Harris-Benedict equation.

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  • Recommendations include hyperproteic intake, limiting glucose to 70% of non-protein calories, lipids to 40%, and increasing antioxidant micronutrients.

    • Impact:

    • Provides a framework for nutritional management in sepsis.
    • Identifies gaps in research regarding the efficacy of nutritional support in sepsis.
    • Suggests potential benefits of pharmaco-nutrient enriched diets, warranting further investigation.