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Updated: Aug 17, 2026

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
Published on: March 30, 2014
Which patients first? Setting priorities for antiretroviral therapy where resources are limited
Laura J McGough1, Steven J Reynolds, Thomas C Quinn
1Department of Infectious Diseases, Johns Hopkins Bayview Medical Center, 4940 Eastern Ave, B-3 North, Baltimore, MD 21224, USA.
Abstract:
The availability of limited funds from international agencies for the purchase of antiretroviral (ARV) treatment in developing countries presents challenges, especially in prioritizing who should receive therapy. Public input and the protection of human rights are crucial in making treatment programs equitable and accountable. By examining historical precedents of resource allocation, we aim to provoke and inform debate about current ARV programs. Through a critical review of the published literature, we evaluate 4 precedents for key lessons: the discovery of insulin for diabetes in 1922, the release of penicillin for civilian use in 1943, the development of chronic hemodialysis programs in 1961, and current allocation of liver transplants. We then describe current rationing mechanisms for ARVs.
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