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Updated: Jul 14, 2026

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
Published on: March 9, 2015
Is baldness bad for the heart?
Thomas Gutersohn1, E Paul Scheidegger
1Department of Dermatology, Kantonsspital Aarau, Aarau, Switzerland. thomas@gutersohn.ch
Certain skin conditions may indicate increased coronary heart disease risk. This review examines potential links between skin signs like earlobe creases and hair patterns and myocardial disease risk, noting methodological flaws in current research.
Area of Science:
- Cardiology
- Dermatology
- Medical Research
Background:
- Established skin markers are linked to coronary disease risk.
- Emerging research suggests other skin signs may also be associated.
- These include horizontal earlobe crease, high breast hair density, early graying, and male pattern hair loss.
Purpose of the Study:
- To review and discuss the relevance of specific skin signs.
- To assess their association with myocardial disease risk.
- To highlight limitations in existing studies.
Main Methods:
- Literature review of studies on skin conditions and coronary disease risk.
- Analysis of reported associations between specific skin signs and myocardial disease.
- Critical evaluation of the methodologies used in the reviewed studies.
Main Results:
- Several skin conditions are recognized indicators of elevated coronary disease risk.
- Evidence suggests potential associations between horizontal earlobe crease, high breast hair density, precocious graying, and male pattern hair loss with myocardial disease.
- However, most existing studies suffer from significant methodological errors.
Conclusions:
- While some skin signs show potential links to coronary disease, more rigorous research is needed.
- Methodological limitations currently hinder definitive conclusions.
- Further well-designed studies are required to validate these associations.
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