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Transfusion associated GVHD

Inderpreet Sohi1, Sunitha Jacob

  • 1Department of Pediatrics, Christian Medical College and Hospital, Ludhiana, Punjab, India. n_kakkar@satyam.net.in

Indian Journal of Pediatrics
|June 30, 2005
PubMed

Transfusion-associated graft-versus-host disease (TA-GVHD) is an under-diagnosed condition in clinical practice. It can occur in immunocompromised as well as immunocompetent hosts and may follow allogeneic bone marrow transplant or transfusion from a related donor. The clinical course is stormy with a high mortality rate. Avoiding the use of blood transfusions from related donors and irradiation of blood products can prevent graft versus host disease. A case of graft versus host disease following related donor transfusion is presented here.

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