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Updated: Aug 20, 2026

Peptides from Phage Display Library Modulate Gene Expression in Mesenchymal Cells and Potentiate Osteogenesis in Unicortical Bone Defects
Published on: December 10, 2010
[Adjuvant therapy (phenol, bone cement) in giant cell tumors]
1Orthopädische Klinik Semmelweis Universität, Budapest, Ungarn.
Abstract:
69 patients were treated with giant-cell tumors in the Orthopaedic Department of the Semmelweis Medical School in Budapest between 1975-1989. The recurrence rate was 15 cases in 36 patients who were treated with curettage and spongiosa plasty only. In 11 cases the curettage was combined with adjuvants (phenol and/or filling with bone cement). This way the recurrence rate could be decreased to 1 case out of 11. The use of phenol and bone cement proved to be useful adjuvants to the surgical curettage at the giant-cell tumors and without complications.
