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Intraocular pressure elevation after intravitreal triamcinolone acetonide injection
Hye Young Park1, Kayoung Yi, Ha Kyoung Kim
1Department of Ophthalmology, Kangnam Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Korea.
Korean Journal of Ophthalmology : KJO
|July 2, 2005
Summary
Intravitreal triamcinolone acetonide (IVTA) injections for macular edema can cause significant intraocular pressure (IOP) elevation, particularly in younger patients. Close IOP monitoring after IVTA treatment is crucial, especially within the first week post-injection.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Pharmacology
Background:
- Macular edema is a significant cause of vision loss.
- Intravitreal triamcinolone acetonide (IVTA) is used to treat macular edema.
- Changes in intraocular pressure (IOP) following IVTA are a concern.
Purpose of the Study:
- To investigate IOP changes after IVTA for macular edema.
- To identify factors influencing IOP elevation post-IVTA.
Main Methods:
- Prospective, non-comparative study of 60 patients.
- All patients received a 4-mg IVTA injection.
- IOP was monitored over time.
Main Results:
- Mean IOP increased post-injection, peaking at 2 months.
- 43.3% of eyes showed significant IOP elevation.
- Younger age was a significant predictor of IOP elevation.
Conclusions:
- IOP spikes can occur within one week in patients requiring surgery.
- Clinicians should monitor IOP at one week post-IVTA.
- Caution is advised for younger patients receiving IVTA.