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Updated: Aug 17, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
A case of congenital corneal keloid
Jong-Suk Song1, Sangwon Kwon, Kyung-Hwan Shyn
1Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea. crisim@korea.ac.kr
Purpose:
To describe a case of unilateral comeal keloid and present the clinical and histopathological findings and the management.
Methods:
A 23-year-old Asian male patient was examined for a white spot on the left cornea that had been present since birth. On biomicroscopic examination, a well-demarcated vascularized comeal mass was found located nasal to the center. The pupil was displaced superiorly, and gonioscopic examination showed peripheral iridocomeal adhesion at 12 o'clock. The patient underwent penetrating keratoplasty.
Results:
Histopathologic study showed a variously thickened epithelial layer, an absence of Bowman's layer, subepithelial fibrovascular hyperplasia, and an absence of dermal elements. These histopathologic findings suggested a congenital comeal keloid. The central graft comea remained clear at 18 months after surgery and the patient was satisfied with the result.
Conclusions:
Penetrating keratoplasty may be an effective surgical option for congenital keloids in young adult patients.

