Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Assays for HIV with improved sensitivity and specificity.

S J Best1, E M Dax

  • 1National Serology Reference Laboratory at Fairfield Hospital, Yarra Bend Road, Fairfield 3078, Australia. sue@nrl.pegasus.oz.au

Expert Opinion on Investigational Drugs
|August 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nonoccupational post-exposure prophylaxis source tracing: is it really feasible in Australia?

HIV medicine·2012
Same author

Canine subcutaneous mast cell tumors: cellular proliferation and KIT expression as prognostic indices.

Veterinary pathology·2010
Same author

Canine subcutaneous mast cell tumor: characterization and prognostic indices.

Veterinary pathology·2010
Same author

An international quality control programme for PRISM chemiluminescent immunoassays in blood service and blood product laboratories.

Vox sanguinis·2009
Same author

Advances in quality assurance of laboratory testing for transfusion safety.

Developments in biologicals·2007
Same author

Quality assessment program for genotypic antiretroviral testing improves detection of drug resistance mutations.

Journal of clinical microbiology·2003
Same journal

Advancements in longevity pharmacology research - are we finally seeing clinical progression?

Expert opinion on investigational drugs·2026
Same journal

Consideration of the use of nalbuphine in idiopathic pulmonary fibrosis-associated cough: to cough or not to cough so much?

Expert opinion on investigational drugs·2026
Same journal

Investigational new drug TAP-1502 beginning clinical study for seborrheic dermatitis.

Expert opinion on investigational drugs·2026
Same journal

Cannabinoid use in adults with sickle cell disease: therapeutic development and clinical insights.

Expert opinion on investigational drugs·2026
Same journal

Odronextamab: a bispecific antibody for follicular lymphoma.

Expert opinion on investigational drugs·2026
Same journal

Evaluating the investigational drug landscape for <i>ESR1</i>-mutated, estrogen receptor-positive, HER2-negative metastatic breast cancer.

Expert opinion on investigational drugs·2026
See all related articles

Understanding human immunodeficiency virus (HIV) evolution and host responses is crucial. Advances in HIV detection assays improve monitoring and treatment, requiring high sensitivity and specificity for viral quantification and host immune markers.

Area of Science:

  • Virology and Immunology
  • Medical Diagnostics

Background:

  • Human immunodeficiency virus (HIV) rapidly mutates, complicating therapeutic monitoring and drug resistance assessment.
  • Understanding viral kinetics and host immune responses is vital for managing HIV infection.
  • Prolific viral replication necessitates accurate measurement of viral burden and immune markers.

Purpose of the Study:

  • To review current knowledge on HIV infection kinetics and pathogenesis.
  • To provide a historical overview of the development of HIV detection assays.
  • To discuss the future of HIV testing in response to evolving viral dynamics and treatment strategies.

Main Methods:

  • Review of existing literature on HIV infection, pathogenesis, and assay development.
  • Analysis of trends in assay sensitivity, specificity, and molecular techniques.

Related Experiment Videos

  • Consideration of in vivo virus dynamics, emerging subtypes, and changing therapeutic approaches.

    • Main Results:

    • Significant advancements in understanding HIV viral parameters and host immune changes.
    • Improvements in the sensitivity and specificity of anti-HIV and HIV detection assays.
    • Development of novel molecular techniques for more sensitive measurement of various parameters.

    Conclusions:

    • Accurate assessment of viral load and immune markers is essential for effective HIV management.
    • Evolving HIV testing strategies must accommodate viral dynamics, new subtypes, and combination therapy.
    • Future HIV assays will require extreme sensitivity and specificity for viral quantification and host response monitoring.