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Published on: October 7, 2025
[Detection of expression of endometriosis-related cytokine and their receptor genes by cDNA microarray technique]
Yang Fan1, Bi-liang Chen, Xiang-dong Ma
1Department of Obstetrics and Gynecology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
Aim:
To study the pathogenesis of endometriosis(EM) by investigating cytokine(CK) and CKR genes expression involved in the development of EM.
Methods:
The CK and CKR gene expression pattern in samples of EM and normal endometrial tissues were analyzed by using cDNA microarrays.
Results:
119 genes were expressed differently between 3 cases EM tissues and 3 cases normal endometria tissues. Among them, 15 were CK and CKR genes, including IL-1, IL-2, IL-6, IL-8, VEGFR, TGF, EGF, FGF, and EPOR etc.
Conclusion:
These 15 differently expressed CK and CKR genes may be correlated with the development of EM.
