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Updated: Jul 19, 2026

Assaying Proteasomal Degradation in a Cell-free System in Plants
Published on: March 26, 2014
A new FronTIR in targeted protein degradation and plant development
Jennifer L Nemhauser1, Joanne Chory
1Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California 92037, USA.
Abstract:
Three papers, two in a recent issue of Nature and one in the July issue of Developmental Cell, identify a family of F box proteins as the long-sought receptors for the plant growth hormone auxin. The new studies reveal that auxin, a small molecule, regulates F box proteins, which are involved in ubiquitin-mediated protein degradation. This finding has profound implications for understanding plant physiology and development and for defining new modes of regulation of SCF ubiquitin ligase complexes.
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