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Related Concept Videos

Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Antiasthma Drugs: Leukotriene Modifiers01:19

Antiasthma Drugs: Leukotriene Modifiers

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Leukotriene modifiers, or cysteinyl leukotriene receptor antagonists, are medications used to manage chronic asthma. These agents target specific inflammatory mediators produced during arachidonic acid metabolism, an essential process in generating inflammation in the body.
Leukotriene modifiers work through two distinct mechanisms:
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Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
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Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
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Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

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The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
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Related Experiment Video

Updated: May 3, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Allergen avoidance in asthma: what do we do now?

George T O'Connor1

  • 1Pulmonary Center, Department of Medicine, Boston University School of Medicine, Boston, MA, USA. goconnor@bu.edu

The Journal of Allergy and Clinical Immunology
|July 2, 2005
PubMed
Summary

Multifaceted home allergen avoidance may benefit asthma patients, but isolated interventions are less effective. Research on infant allergen avoidance for primary asthma prevention is ongoing.

Area of Science:

  • Environmental Health
  • Allergy and Immunology
  • Pulmonary Medicine

Background:

  • Allergen exposure exacerbates asthma in sensitized individuals.
  • Optimal allergen avoidance strategies for asthma management remain controversial.
  • The efficacy of single, targeted interventions is often limited.

Purpose of the Study:

  • To evaluate the clinical efficacy of allergen avoidance interventions in asthma patients.
  • To determine the effectiveness of multifaceted versus narrow environmental interventions.
  • To assess the role of infant allergen avoidance in primary asthma prevention.

Main Methods:

  • Review of recent evidence on home-based environmental interventions.
  • Analysis of studies on single allergen avoidance measures (e.g., mattress covers).

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  • Evaluation of preliminary data on primary asthma prevention through infant allergen avoidance.

    • Main Results:

    • Multifaceted, home-based environmental interventions targeting multiple allergens show potential clinical benefits.
    • Narrow interventions, such as mattress covers alone, may provide minimal benefit.
    • Data on infant allergen avoidance for primary prevention are currently insufficient for recommendations.

    Conclusions:

    • A comprehensive, home-based environmental approach is more promising for asthma management than isolated interventions.
    • Further research is needed to establish definitive public health recommendations for infant allergen avoidance in asthma prevention.