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Published on: September 21, 2015
Supraumbilical pyloromyotomy: a unique indication for antimicrobial prophylaxis
Alan P Ladd1, Shari A Nemeth, Anna N Kirincich
1Division of Pediatric Surgery, Riley Hospital for Children, Indianapolis, IN 46202, USA. aladd@iupui.edu
Insights
The supraumbilical approach for pyloromyotomy in infantile hypertrophic pyloric stenosis increases infection risk. Prophylactic antibiotics effectively reduce wound infections, making the approach safer for pediatric patients.
Area of Science:
- Pediatric Surgery
- Surgical Infections
- Pyloric Stenosis
Background:
- The umbilical fold incision for infantile hypertrophic pyloric stenosis offers cosmetic benefits and convenient surgical exposure.
- This study compares infection rates between traditional and supraumbilical pyloromyotomy approaches.
Purpose of the Study:
- To investigate the difference in wound infection rates between traditional and supraumbilical pyloromyotomy techniques.
- To evaluate the impact of prophylactic antibiotics on infection rates in supraumbilical pyloromyotomy.
Main Methods:
- A retrospective review of 384 patients undergoing pyloromyotomy for infantile hypertrophic pyloric stenosis.
- Comparison of infection rates across three groups: right upper quadrant incision (group 1), supraumbilical incision (group 2), and supraumbilical incision with prophylactic antibiotics (group 3).
Main Results:
- The infection rate for the traditional right upper quadrant incision was 2.3%.
- The supraumbilical approach showed a significant increase in infection rate to 7.0%.
- Prophylactic antibiotics reduced the supraumbilical approach infection rate to 2.3%, comparable to the traditional method.
Conclusions:
- The open supraumbilical approach for pyloromyotomy significantly increases the risk of wound infection compared to the traditional method.
- Prophylactic antibiotic administration effectively mitigates the increased infection risk associated with the supraumbilical approach.
Background:
The umbilical fold incision for infantile hypertrophic pyloric stenosis provides a convenient exposure and cosmetically appealing scar. This study investigates the possible difference in infection rates between traditional and supraumbilical approaches for pyloromyotomy.
Methods:
All patients who underwent pyloromyotomy for infantile hypertrophic pyloric stenosis at a tertiary pediatric hospital were reviewed. Baseline wound infection rate was determined through review of patients with right upper quadrant incisions (group 1). A nonrandomized comparison was performed between patients with a supraumbilical approach (group 2) and those undergoing supraumbilical incisions after prophylactic antibiotic administration (group 3).
Results:
Complete records were reviewed on 384 patients over a 6-year period. Demographics and preoperative factors were similar among groups. The rate of infection in group 1 (n = 258) was 2.3%. With introduction of the supraumbilical approach, there was a statistically significant increase in wound infection rate to 7.0% (chi 2 ; group 1 vs group 2, P < .05). The use of prophylactic antibiotics with a supraumbilical approach reduced this rate of infection back to 2.3% (chi 2 ; group 1 vs group 3, P < 1.0 and group 2 [n = 85] vs group 3 [n = 42], P < .3).
Conclusions:
The risk of wound infection by classic pyloromyotomy of 2.3% is significantly increased with an open supraumbilical approach. The use of prophylactic antibiotics reduces this risk of wound infection.
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