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39th Interscience Conference on Antimicrobial Agents and Chemotherapy of the American Society for Microbiology

L E Lawrence1, M J Pucci, M Frosco

  • 1Bristol-Myers Squibb, 5 Research Parkway, Wallingford, CT 06492, USA.

Expert Opinion on Investigational Drugs
|July 5, 2005
PubMed

Insights

The 39th ASM ICAAC Meeting showcased late-stage antibacterials, with quinolones like moxifloxacin and gatifloxacin being most prominent. Resistance emergence remains a key concern, driving research into novel antibiotic development.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Pharmacology

Background:

  • The 39th ASM ICAAC Meeting convened over 16,000 delegates to discuss advancements in antibacterial research.
  • Over 600 reports addressed the critical issue of antibiotic resistance emergence and its global impact on susceptibility patterns.

Purpose of the Study:

  • To summarize the key antibacterial agents and research trends presented at the 39th ASM ICAAC Meeting.
  • To highlight the prevalence of established antibacterial classes and emerging resistance concerns.

Main Methods:

  • Analysis of presentations (posters, symposia, oral) from the 39th ASM ICAAC Meeting.
  • Categorization of presented antibacterials by class and specific agents.
  • Identification of research focus areas, particularly resistance emergence.

Main Results:

  • Established antibacterial classes, including quinolones, beta-lactams, protein synthesis inhibitors, and carbapenems, were most frequently presented.
  • Quinolones, specifically moxifloxacin, gatifloxacin, and gemifloxacin, dominated the conference presentations.
  • The oxazolidinone class, represented by Linezolid, was also a notable focus.

Conclusions:

  • The conference underscored the ongoing challenge of antibiotic resistance and the need for continued development of effective treatments.
  • Established antibacterial classes remain central to research efforts, with quinolones showing significant attention.
  • Novel antibiotic classes like oxazolidinones represent a promising avenue for addressing resistant bacterial infections.

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