Related Experiment Video
Updated: Aug 17, 2026
Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
Limbal allograft, amniotic membrane transplantation, and intraoperative mitomycin C for recurrent pterygium
Takashi Miyai1, Ryuhei Hara, Ryohei Nejima
1Miyata Eye Hospital, Tokyo, Japan.
Objective:
To conduct a pilot study evaluating the efficacy and safety of limbal allograft, preserved amniotic membrane transplantation, and intraoperative mitomycin C treatment for recurrent pterygium.
Design:
Prospective, noncomparative, interventional case series.
Participants:
Twelve eyes of 11 patients with recurrent pterygium. The mean number of previous surgeries for pterygium was 1.9+/-1.4 (range, 1-6).
Intervention:
All subjects received limbal allograft, preserved amniotic membrane transplantation, and intraoperative mitomycin C.
Main Outcome Measures:
Pterygium recurrence and complications.
Results:
The mean follow-up period was 21.6+/-5.6 months (range, 16-36 months). There was no pterygium recurrence in any of the eyes. Symblepharon reappeared in 3 eyes and diplopia recurred in 2 eyes. There were no other surgical complications and there was no graft rejection.
Conclusions:
Limbal allograft, preserved amniotic membrane transplantation, and intraoperative mitomycin C may be a safe and effective procedure for recurrent pterygium.
