Related Experiment Video
Updated: Aug 17, 2026

Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs
Published on: May 10, 2018
TICO: a tool for improving predictions of prokaryotic translation initiation sites
Maike Tech1, Nico Pfeifer, Burkhard Morgenstern
1Abteilung Bioinformatik, Institut für Mikrobiologie und Genetik, Georg-August-Universität Göttingen Goldschmidtstrasse 1, 37077 Göttingen, Germany. maike@gobics.de
Unlabelled:
We provide the tool 'TICO' (Translation Initiation site COrrection) for improving the results of conventional gene finders for prokaryotic genomes with regard to exact localization of the translation initiation site (TIS). At the current state TICO provides an interface for direct post processing of the predictions obtained from the widely used program GLIMMER. Our program is based on a clustering algorithm for completely unsupervised scoring of potential TIS locations.
Availability:
Our tool can be freely accessed through a web interface at http://tico.gobics.de/
Contact:
maike@gobics.de
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