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TO-GO: a Java-based Gene Ontology navigation environment.

Ungsik Yu1, Yoon Jeong Choi, Jung Kyoon Choi

  • 1National Genome Information Center, KRIBB, Oun 52, Yusong, Daejeon 305-333, Korea. ungsik@kribb.re.kr

Bioinformatics (Oxford, England)
|July 5, 2005
PubMed
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TO-GO is a Java application for navigating the Gene Ontology (GO) database. This tool allows for interactive exploration of GO terms and gene product information, with offline capabilities and data analysis features.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genomics

Background:

  • Gene Ontology (GO) provides a structured vocabulary for gene product function.
  • Efficient navigation and analysis of GO data are crucial for biological research.
  • Existing tools may lack interactive features or offline capabilities.

Purpose of the Study:

  • To introduce TO-GO, a novel Gene Ontology navigation tool.
  • To provide an interactive and efficient platform for GO term and gene product data exploration.
  • To facilitate data analysis, including set operations for expression profile data.

Main Methods:

  • TO-GO is a Java application enabling interactive GO term tree navigation.
  • Supports offline access after initial data download.

Related Experiment Videos

  • Incorporates local annotation and querying by GO terms or gene products.
  • Provides results in tabular or sub-tree formats.
  • Implements set operations for advanced data analysis.
  • Main Results:

    • Interactive navigation of the GO term tree without network dependency.
    • Display of gene products associated with GO terms, including hierarchical counts.
    • Facilitation of data exchange through copy/paste functionality.
    • Utility of set operations for expression profile data analysis.

    Conclusions:

    • TO-GO offers an efficient and user-friendly interface for Gene Ontology exploration.
    • The tool enhances biological data analysis through interactive features and offline access.
    • TO-GO supports integration with local data and facilitates data sharing.