Specificity constants in the context of protein engineering of two-substrate enzymes

Allosteric behaviour of 1:5 hybrids of mutant subunits of Clostridium symbiosum glutamate dehydrogenase differing in their amino acid specificity.

The Biochemical journal·2001

Conversion of a glutamate dehydrogenase into methionine/norleucine dehydrogenase by site-directed mutagenesis.

European journal of biochemistry·2001

Purification and characterisation of a serine peptidase from the marine psychrophile strain PA-43.

FEMS microbiology letters·2001

Characterization of alanine and malate dehydrogenases from a marine psychrophile strain PA-43.

Extremophiles : life under extreme conditions·2001

Contribution of an aspartate residue, D114, in the active site of clostridial glutamate dehydrogenase to the enzyme's unusual pH dependence.

Biochimica et biophysica acta·2001

Construction, separation and properties of hybrid hexamers of glutamate dehydrogenase in which five of the six subunits are contributed by the catalytically inert D165S.

European journal of biochemistry·2001

KDM2B controls HIF levels and activity through its JmjC and CxxC domains.

The Biochemical journal·2026

Graph-based representations in modern protein science.

The Biochemical journal·2026

Probing biomolecular condensates with a minimally perturbative experimental readout framework.

The Biochemical journal·2026

SF3B4 "reads" RNA that is methylated by METTL16.

The Biochemical journal·2026

The non-canonical CDK2 activator SPY1 uses separable mechanisms to activate phosphorylated and unphosphorylated CDK2.

The Biochemical journal·2026

Bisecting GlcNAc in N-glycan regulates synaptic maturation.

The Biochemical journal·2026

Photothermal CO2 hydrogenation for C1 fuels: fundamentals, reaction pathways and reactor design.

Chemical communications (Cambridge, England)·2026

From electromagnetic field-material interactions to intensified chemical manufacturing via microwave catalysis.

Chemical Society reviews·2026

Enhanced methane selectivity by electrochemical CO2 reduction at a choline-alaninate/Au(111) interface: DFT and microkinetic insights.

Physical chemistry chemical physics : PCCP·2026

Biomimetic spatial compartmentalization directs C1 intermediate evolution for highly selective CO2 photomethanation.

Chemical science·2026

A Stereoconvergent Annulation in the Synthesis of Lysergic Acid.

Synthesis·2026

Space-velocity-governed chemoselective pseudo-oxidation: a convergent flow platform for the synthesis of evocalcet.

RSC advances·2026

Related Experiment Videos

Specificity constants in the context of protein engineering of two-substrate enzymes

Related Concept Videos

Allosteric behaviour of 1:5 hybrids of mutant subunits of Clostridium symbiosum glutamate dehydrogenase differing in their amino acid specificity.

Conversion of a glutamate dehydrogenase into methionine/norleucine dehydrogenase by site-directed mutagenesis.

Purification and characterisation of a serine peptidase from the marine psychrophile strain PA-43.

Characterization of alanine and malate dehydrogenases from a marine psychrophile strain PA-43.

Contribution of an aspartate residue, D114, in the active site of clostridial glutamate dehydrogenase to the enzyme's unusual pH dependence.

Construction, separation and properties of hybrid hexamers of glutamate dehydrogenase in which five of the six subunits are contributed by the catalytically inert D165S.

KDM2B controls HIF levels and activity through its JmjC and CxxC domains.

Graph-based representations in modern protein science.

Probing biomolecular condensates with a minimally perturbative experimental readout framework.

SF3B4 "reads" RNA that is methylated by METTL16.

The non-canonical CDK2 activator SPY1 uses separable mechanisms to activate phosphorylated and unphosphorylated CDK2.

Bisecting GlcNAc in N-glycan regulates synaptic maturation.

Photothermal CO2 hydrogenation for C1 fuels: fundamentals, reaction pathways and reactor design.

From electromagnetic field-material interactions to intensified chemical manufacturing via microwave catalysis.

Enhanced methane selectivity by electrochemical CO2 reduction at a choline-alaninate/Au(111) interface: DFT and microkinetic insights.

Biomimetic spatial compartmentalization directs C1 intermediate evolution for highly selective CO2 photomethanation.

A Stereoconvergent Annulation in the Synthesis of Lysergic Acid.

Space-velocity-governed chemoselective pseudo-oxidation: a convergent flow platform for the synthesis of evocalcet.

Related Experiment Videos

Specificity constants in the context of protein engineering of two-substrate enzymes

Related Concept Videos

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