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Updated: Aug 17, 2026

Comparative Lesions Analysis Through a Targeted Sequencing Approach
08:16

Comparative Lesions Analysis Through a Targeted Sequencing Approach

Published on: November 5, 2019

[Prospect of uses of single nucleotide polymorphism in the neoplasm research ]

Dong-xin Lin, Tong Sun

    Zhonghua Zhong Liu Za Zhi [Chinese Journal of Oncology]
    |July 6, 2005
    PubMed
    Abstract

    No abstract available in PubMed .

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    A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...