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Updated: Aug 17, 2026
In Vitro Culture of Epithelial Cells from Different Anatomical Regions of the Human Amniotic Membrane
Published on: November 28, 2019
Amniotic membrane for cervical reconstruction
1St. John's Medical College, Bangalore-560 034, India. ritamhaskar@yahoo.com
Objective:
To evaluate the use of amniotic membrane grafts in cases of vaginal and cervical agenesis.
Methods:
Five girls with complete cervical and vaginal agenesis underwent cervicoplasty and vaginoplasty using amniotic membrane grafts.
Result:
Excellent epithelization and patency of cervix and vagina was achieved in all cases.
Conclusion:
Amniotic membrane may be used as an allograft in cervical reconstruction. It is inexpensive, readily available, of low antigenicity and does not necessitate repeated cervical dilatation. The performance of the reconstructed cervix during labor is yet to be observed. To the author's knowledge, this is the first series reported in the literature in which amniotic membrane was used for cervical reconstruction.
