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The Clinical Application of Tumor Treating Fields Therapy in Glioblastoma
Published on: April 16, 2019
[Temozolomide in patients with a glioblastoma multiforme: new developments]
1Erasmus MC, locatie Daniel den Hoed Oncologisch Centrum, afd. Neurooncologie, Postbus 5201, Rotterdam. j.bromberg@erasmusmc.nl
Abstract:
There are new scientific data concerning the treatment of patients with glioblastoma multiforme with concomitant and adjuvant temozolomide following surgery and radiotherapy. Patients have an improved survival rate, especially if they also have a methylated promoter of the methylguanine-DNA-methyltransferase (MGMT) gene. It is advisable to consider treating young patients with primary glioblastoma multiforme who are in good condition with concomitant and adjuvant temozolomide. Efficacy of temozolomide in recurrent glioblastoma multiforme is limited.
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