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Updated: Aug 9, 2026

Intracavernosal Pressure Recording to Evaluate Erectile Function in Rodents
Published on: June 6, 2018
[Advances in application of sildenafil to erectile dysfunction]
Zheng Li1, Zheng-Mu Wu, Yi-Xin Wang
1Shanghai Institute of Andrology, Renji Hospital Affiliated to Shanghai Second Medical University, Shanghai 200001, China. sperm_lee@yahoo.com
Abstract:
Since the worldwide introduction of sildenafil in 1998, 23 million patients with ED have been treated with the drug, and the accumulated experiences have proved its safety and efficacy. This article presents a review about the action mechanism and metabolic process of sildenafil, with a particular focus on the application of sildenafil to ED diagnosis, the curative effect of its daily use on ED, the standard treatment, combined therapy and progressive protocol with sildenafil for ED and its complications, along with such safety aspect as its effect on the sight.
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