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Measuring Changes in Tactile Sensitivity in the Hind Paw of Mice Using an Electronic von Frey Apparatus
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Inhibitory effect of whole bee venom in adjuvant-induced arthritis

Jae Yeong Lee1, Seong Soo Kang, Joong-Hyun Kim

  • 1College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University, Republic of Korea.

In Vivo (Athens, Greece)
|July 8, 2005
PubMed

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Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
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Local anesthetics (LAs) block sensory and motor impulses by inhibiting the sodium channels on the nerve cell membranes. This induces temporary loss of sensation, relieving pain in a specific body area.
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