Related Experiment Videos
An update on the functional molecular immunology (FIMM) database
Christian Schönbach1, Judice L Y Koh, Darren R Flower
1Knowledge Discovery Department, Institute for Infocomm Research, Singapore.
Applied Bioinformatics
|July 8, 2005
Summary
The Functional molecular IMMunology (FIMM) database integrates scattered immunological data. This resource aids researchers in understanding immune responses, discovering vaccine targets, and studying immune diseases.
Area of Science:
- Immunology
- Bioinformatics
- Computational Biology
Background:
- Immunological data, including major histocompatibility complex (MHC) and epitope information, is fragmented across diverse databases and literature.
- This fragmentation hinders a comprehensive understanding of functional immune response components and their roles in health and disease.
Purpose of the Study:
- To develop and maintain the Functional molecular IMMunology (FIMM) database, providing an integrated resource for immunological data.
- To facilitate easier access to curated information on protein antigens and human immunological receptors.
Main Methods:
- Expert curation of data on protein antigens and human immunological receptors.
- Development of intuitive query interfaces and reporting tools for data retrieval and interpretation.
Main Results:
- The FIMM database integrates heterogeneous data on MHC, T-cell epitopes, B-cell epitopes, antigens, and diseases.
- Provides expert-curated information on protein antigens and their corresponding human immunological receptors.
Conclusions:
- The FIMM database offers a centralized, integrated view of functional immune response components.
- Facilitates data interpretation, accelerates vaccine target discovery, and supports immune disease research for immunologists.