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wolfPAC: building a high-performance distributed computing network for phylogenetic analysis using 'obsolete'

Patrick A Reeves1, Philip H Friedman, Christopher M Richards

  • 1United States Department of Agriculture, Agricultural Research Service (USDA-ARS), National Center for Genetic Resources Preservation, Fort Collins, Colorado 80521, USA.

Applied Bioinformatics
|July 8, 2005
PubMed
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wolfPAC software enables distributed phylogenetic analysis on multiple Macintosh computers using PAUP*. This approach leverages inexpensive processors to foster resource sharing within the global phylogenetics community.

Area of Science:

  • Computational Biology
  • Bioinformatics
  • Evolutionary Biology

Background:

  • Phylogenetic analyses require significant computational resources.
  • Distributed computing offers a scalable solution for intensive tasks.
  • Existing methods may not fully utilize available networked hardware.

Purpose of the Study:

  • To introduce wolfPAC, a novel software package for distributed phylogenetic analysis.
  • To enable the use of multiple, geographically dispersed Macintosh computers for phylogenetic computations.
  • To promote resource sharing and collaboration in the phylogenetics research community.

Main Methods:

  • Utilizes AppleScript for inter-computer communication and task distribution.
  • Integrates with PAUP* (Phylogenetic Analysis Using Parsimony) for core phylogenetic analyses.

Related Experiment Videos

  • Designed for deployment on readily available and inexpensive Macintosh hardware.
  • Main Results:

    • Facilitates computationally intensive phylogenetic analyses through distributed processing.
    • Demonstrates the feasibility of using a network of Macintosh computers for complex biological research.
    • Provides a framework for efficient utilization of shared computational resources.

    Conclusions:

    • wolfPAC offers an accessible and cost-effective solution for advancing phylogenetic research.
    • The software encourages a collaborative approach to computational challenges in phylogenetics.
    • Distributed computing with wolfPAC can significantly accelerate the pace of evolutionary studies.