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Published on: April 9, 2012
Does resistance to pyrazinamide accurately indicate the presence of Mycobacterium bovis?
Bouke C de Jong1, Anthony Onipede, Alex S Pym
1Division of Infectious Diseases, Stanford University, Stanford, California, USA. bouke@stanford.edu
Journal of Clinical Microbiology
|July 8, 2005
Abstract:
Mycobacterium bovis is best identified by screening those isolates of the Mycobacterium tuberculosis complex that have any pyrazinamide (PZA) resistance, using a confirmatory test such as spoligotyping, biochemical testing, or genomic deletion analysis. The sensitivity for detection of M. bovis is lowered to 82% when only PZA-monoresistant isolates are screened.
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