Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Does somatosensory amplification decrease with antidepressant treatment?

Kemal Sayar1, Arthur J Barsky, Huseyin Gulec

  • 1Bakirkoy Mental Health Training and Research Hospital, Istanbul, Turkey. kemalsayar@hotmail.com

Psychosomatics
|July 8, 2005
PubMed
Summary

Antidepressant therapy reduced somatosensory amplification in major depression patients but not in fibromyalgia patients. Further research is needed to clarify the relationship between somatosensory amplification and depression.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of likelihood framing on side effect expectations and nocebo side effects: Results from three experimental studies with a placebo analgesic cream.

British journal of health psychology·2026
Same author

Agitation and Aggression in Psychiatric Care: Insights From Nursing Observations in a Turkish Mental Health State Hospital.

Journal of psychiatric and mental health nursing·2025
Same author

The Relationship of Personality Organization and Resilience With Treatment Motivation and Early Recovery Rates in Patients With Opioid and Polysubstance Use Disorders.

Substance use & misuse·2025
Same author

Self-compassion, emotion regulation, and resilience as predictors of psychological well-being in fibromyalgia patients: a cross-sectional study.

Rheumatology international·2025
Same author

Polysomnographic and clinical characteristics of sleep apnea headache patients.

Sleep & breathing = Schlaf & Atmung·2024
Same author

Validity, Reliability, and Factor Structure of the Suicide Crisis Scale in Turkish.

Alpha psychiatry·2024

Area of Science:

  • Psychiatry
  • Psychosomatic Medicine
  • Clinical Psychology

Background:

  • Somatosensory amplification is characterized by heightened perception of bodily sensations.
  • Its stability and response to treatment remain areas of investigation, particularly in relation to mood disorders.

Purpose of the Study:

  • To investigate the impact of antidepressant therapy on somatosensory amplification.
  • To determine if somatosensory amplification is a stable trait or mutable with treatment in patients with major depressive disorder and fibromyalgia.

Main Methods:

  • Fifteen fibromyalgia patients and 17 major depressive disorder patients underwent antidepressant treatment.
  • Somatosensory amplification, depression, and anxiety levels were assessed at baseline, 6 weeks, and 12 weeks.

Related Experiment Videos

Main Results:

  • Somatosensory amplification scores improved in major depressive disorder patients but not in fibromyalgia patients.
  • Despite decreased depression in both groups, amplification changes in fibromyalgia were not significant.
  • After controlling for changes in depression and anxiety, amplification scores did not change significantly in either group.

Conclusions:

  • Antidepressant treatment may influence somatosensory amplification in major depression, but not in fibromyalgia.
  • The independence of somatosensory amplification from depression requires further investigation in larger, more definitive studies.