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Combined Supine and Standing Imaging for Varicocele: An Improved Diagnostic Approach
Published on: November 22, 2024
Increased prevalence of varicocele in patients with coronary artery ectasia
Ertan Yetkin1, Suleyman Kilic, Nusret Acikgoz
1Department of Cardiology, Inonu University School of Medicine, Malatya, and Diyarbakir Government Hospital, Department of Urology, Diyarbakir, Turkey. eryetkin@ttnet.net.tr
Insights
Patients with coronary artery ectasia (CAE) have a significantly higher prevalence of varicocele, a venous dilatation, compared to those with coronary artery disease. This suggests a potential link between the underlying mechanisms of CAE and varicocele development.
Area of Science:
- Cardiology
- Vascular Medicine
- Urology
Background:
- Coronary artery ectasia (CAE) involves non-obstructive dilation of coronary arteries.
- Varicocele is characterized by the dilatation of the pampiniform plexus.
- Previous studies noted a higher prevalence of peripheral varicose veins in CAE patients.
Purpose of the Study:
- To investigate the prevalence of varicocele in patients diagnosed with coronary artery ectasia (CAE).
- To compare varicocele prevalence between patients with CAE and those with coronary artery disease (CAD).
Main Methods:
- A cohort of 35 male patients with CAE (with or without CAD) was compared to 63 age-matched male patients with CAD.
- All participants underwent evaluation for the presence of varicocele.
Main Results:
- Varicocele was detected in 62% of patients with CAE.
- Varicocele was found in 38% of patients with CAD.
- The difference in varicocele prevalence between the groups was statistically significant (P=0.02).
Conclusions:
- Coronary artery ectasia patients exhibit a higher prevalence of varicocele than patients with coronary artery disease.
- The underlying mechanisms of CAE may predispose individuals to developing varicocele.
Background:
Coronary artery ectasia (CAE) is defined as localized or diffuse non-obstructive lesions of the epicardial coronary arteries with a luminal dilation exceeding the 1.5-fold of normal adjacent segment or vessel diameter. Varicocele is the dilatation of the pampiniform plexus. Recently increased prevalence of peripheral varicose veins has been shown in patients with CAE. In this study we aimed to assess the prevalence of varicocele, which is dilatation of another venous system, in patients with CAE.
Materials And Methods:
Thirty-five male consecutive patients with coronary artery ectasia in combination with or without coronary artery disease (CAD) and 63 male, age-matched patients with coronary artery disease were included in the study. All patients were evaluated for the presence of varicocele.
Results:
Twenty-one patients with CAE were found to have varicocele (62% of group I patients). In patients with CAD, 24 patients (38%) were found to have varicocele. The difference between the two groups in respect to presence of varicocele was statistically significant (P=0.02; odds ratio=1.57; 95% confidence interval 1.05- 2.3).
Conclusion:
We have shown that patients with coronary artery ectasia have an increased prevalence of varicocele compared to those with coronary artery disease. The mechanism underlying coronary artery ectasia might further increase the prevalence of varicocele in susceptible patients.
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