How and when to use mitomycin-C in refractive surgery
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Updated: Aug 17, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
Published on: September 20, 2024
Gaston O Lacayo1, Parag A Majmudar
1Department of Ophthalmology, Rush University Medical Center, Chicago, Illinois, USA.
Purpose Of Review:
Mitomycin-C is an antimetabolite that has seen increased use in ophthalmology over the past several decades. From glaucoma surgery to the management of various corneal disorders, mitomycin-C seems to be a viable tool in the management of scar and haze formation.
Recent Findings:
With the constant evolution of refractive surgery, mitomycin-C has come to the forefront as a modulator of corneal wound healing after excimer laser surface ablation.
Summary:
This article will describe the various indications, techniques, and current trends of mitomycin-C application in corneal refractive surgery.
