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Craniopharyngiomas in children: Turkey experience
Yusuf Erşahin1, Taskin Yurtseven, Erkin Ozgiray
1Division of Pediatric Neurosurgery, Ege University Faculty of Medicine, 35100, Bornova, Izmir, Turkey. ersahin@med.ege.edu.tr
Summary
Pediatric craniopharyngioma treatment requires individualized, multidisciplinary care. Gross total tumor removal is crucial for better outcomes, while larger tumor size correlates with worse prognosis in children.
Area of Science:
- Pediatric Neurosurgery
- Pediatric Oncology
- Tumor Biology
Background:
- Craniopharyngiomas are common pediatric suprasellar tumors.
- Achieving complete tumor resection without complications is challenging.
Purpose of the Study:
- To review treatment outcomes for pediatric craniopharyngioma patients across eight Turkish institutions.
- To identify factors influencing treatment success and prognosis.
Main Methods:
- Retrospective analysis of 87 pediatric craniopharyngioma cases (51 boys, 36 girls).
- Data collected on patient demographics, symptoms, tumor characteristics, treatment, and outcomes.
- Statistical analysis to determine significant factors affecting outcomes.
Main Results:
- Headache and visual disturbances were the most frequent symptoms.
- Tumor size >4 cm was linked to hydrocephalus and worse outcomes.
- Recurrence rates were higher with subtotal or partial tumor removal (28%).
- Outcomes improved in patients older than 10 years.
Conclusions:
- Individualized, multidisciplinary treatment approaches are essential.
- The primary surgical goal should be gross total resection with acceptable morbidity and no mortality.
- Tumor dimension and patient age are significant prognostic factors.