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Related Experiment Videos

Primary hepatic carcinoid tumor (a case report).

Toshihiko Kohashi1, Toshiyuki Itamoto, Koji Katayama

  • 1Second Department of Surgery, Hiroshima University School of Medicine, Hiroshima, Japan. cem08830@nyc.odn.ne.jp

Hepato-Gastroenterology
|July 9, 2005
PubMed
Summary

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This report details a rare case of primary hepatic carcinoid tumor in a 77-year-old woman. Surgical resection was successful, highlighting the importance of accurate diagnosis for this uncommon liver malignancy.

Area of Science:

  • Gastroenterology
  • Oncology
  • Pathology

Background:

  • Primary hepatic carcinoid tumors are exceptionally rare.
  • Carcinoid tumors typically originate in the neuroendocrine system, most commonly in the gastrointestinal tract or lungs.

Observation:

  • A 77-year-old woman presented with a large tumor in the right lobe of her liver.
  • Microscopic examination revealed tumor cells with characteristic features of carcinoid tumors, including specific staining patterns.
  • Immunohistochemical analysis showed positivity for neuron-specific enolase and synaptophysin.

Findings:

  • The liver tumor was diagnosed as a primary carcinoid tumor after excluding other potential origins.
  • The tumor exhibited trabecular, glandular, and rosette patterns under light microscopy.

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  • Tumor cells showed variable positivity for chromogranin and carcinoembryonic antigen.

    • Implications:

    • This case underscores the possibility of primary carcinoid tumors originating in the liver.
    • Accurate immunohistochemical staining is crucial for diagnosing rare hepatic neoplasms.
    • Further research into the pathogenesis and management of primary hepatic carcinoid tumors is warranted.