Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The internal capsule in neonatal imaging.

Frances M Cowan1, Linda S de Vries

  • 1Department of Paediatrics, Imperial College, Hammersmith Hospital, London, UK. f.cowan@imperial.ac.uk

Seminars in Fetal & Neonatal Medicine
|July 9, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sustaining progress in HIV care in Africa with a transition to enabled self-care: a modelling study.

The Lancet. Global health·2026
Same author

Economic barriers to diagnostic equity: A multi-country analysis of patient costs for rapid SARS-CoV-2 testing in sub-Saharan Africa.

PloS one·2026
Same author

Development of a modular neonatal neurological examination: from a short screening test to a detailed assessment of specific aspects of neurological function.

European journal of pediatrics·2026
Same author

Prevalence and factors associated with sexually transmitted infections and engagement in HIV care among female sex workers in two large cities of Zimbabwe: Analysis of respondent-driven sampling surveys in 2023.

Sexually transmitted infections·2026
Same author

How good is a simple MRI score for predicting cerebral palsy and more?

Developmental medicine and child neurology·2026
Same author

HIV Prevalence, Virological Suppression, and Consistent Condom Use Among Social Venue-Going Men in Zimbabwe: Insights from the 2022 Priorities for Local AIDS Control Efforts (PLACE) Surveys.

AIDS and behavior·2026

The internal capsule

Area of Science:

  • Neuroimaging
  • Developmental Neuroscience
  • Pediatric Neurology

Background:

  • The internal capsule is a critical white matter tract in the brain, essential for motor and sensory pathways.
  • Its rapid myelination at term and well-documented maturation course make it a key area of study.
  • Abnormalities in the internal capsule on magnetic resonance imaging (MRI) correlate with motor outcomes, particularly in perinatal contexts.

Purpose of the Study:

  • To highlight the significance of the internal capsule in neuroimaging and its predictive value for motor outcomes.
  • To explore advancements in assessing internal capsule maturation and connectivity using diffusion imaging techniques.
  • To understand the impact of preterm birth and hypoxic-ischaemic injury on internal capsule development.

Main Methods:

Related Experiment Videos

  • Conventional magnetic resonance imaging (MRI) for visualizing the internal capsule.
  • Diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) for advanced assessment of maturation and connectivity.
  • Correlation of imaging findings with clinical situations in perinatal medicine and motor outcomes.

Main Results:

  • Conventional MRI effectively visualizes the internal capsule, with its appearance predicting motor outcomes.
  • Normal MRI appearance at term generally associates with normal motor function.
  • Advanced diffusion imaging techniques provide sophisticated insights into internal capsule maturation and connectivity, especially concerning preterm birth and hypoxic-ischaemic injury.

Conclusions:

  • The internal capsule's appearance on conventional MRI is a valuable predictor of motor outcome in perinatal conditions.
  • Diffusion imaging offers enhanced understanding of internal capsule development and its disruption by adverse perinatal events.
  • Future research will extend the assessment of internal capsule findings to cognitive, visual, and sensory abilities.