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[Management of primary vesicoureteral reflux in children]
1Universitatea de Medicină si Farmacie Gr.T.Popa Iaşi, Facultatea de Medicină, Clinica IV Pediatrie.
Insights
Management of primary vesicoureteral reflux (VUR) in children now prioritizes medical treatment to prevent urinary tract infections and kidney scarring. Continuous antibiotic prophylaxis and monitoring for spontaneous resolution are preferred, with surgery reserved for select cases.
Area of Science:
- Pediatric Urology
- Nephrology
- Infectious Disease Management
Context:
- Primary vesicoureteral reflux (VUR) management in children has evolved significantly.
- Focus has shifted towards non-surgical interventions to prevent complications.
Purpose:
- To outline current best practices in pediatric VUR management.
- To highlight the role of medical treatment in preventing urinary tract infections (UTIs) and renal scarring.
- To discuss the evolving role of surgery and emerging minimally invasive techniques.
Summary:
- Current VUR management emphasizes medical treatment, including continuous antibiotic prophylaxis and serial cystography, to monitor for spontaneous resolution.
- This approach aims to prevent UTIs and subsequent post-infectious renal scars.
- Surgical intervention is now reserved for specific, selected cases, with sub-ureteral injection of bulking agents showing promise as a less invasive alternative.
Impact:
- This shift in management aims to reduce long-term renal damage in children with VUR.
- It promotes a conservative approach, minimizing surgical risks and improving patient outcomes.
- Further research into optimal bulking agents is needed to refine minimally invasive treatment options.
Abstract:
The management of primary vesicoureteral reflux (VUR) in child suffered major changes by focusing on the medical treatment in order to prevent the urinary tract infections and the occurrence of postinfectious renal scars. Continuous antibiotic prophylaxis and the follow-up by serial cystography of the spontaneous resolution of the reflux are considered nowadays the best choice in most of the cases. Surgery is recommended only in selected cases. Sub-ureteral injection of bulking agents to correct the reflux holds promise as an alternative to open surgery, but presents the challenge of identifying the ideal bulking agent.
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