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Updated: Aug 17, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
Frequency of pharyngeal reflux in children with adenoid hyperplasia
Bahar Keles1, Kayhan Ozturk, Hamdi Arbag
1Department of Otolaryngology, Meram Medical Faculty, Selcuk University, 42090 Meram, Konya, Turkey. baharkeles@hotmail.com
Insights
Children with adenoid hyperplasia show a higher frequency of pharyngeal reflux. This suggests that pharyngeal reflux may contribute to the development of adenoid hyperplasia in pediatric patients.
Area of Science:
- Pediatric Otolaryngology
- Gastroenterology
- Respiratory Medicine
Background:
- Adenoid hyperplasia is a common condition in children, often associated with upper airway obstruction.
- Pharyngeal reflux, a form of gastroesophageal reflux (GER), involves the backflow of stomach contents into the pharynx.
- The potential link between pharyngeal reflux and adenoid hyperplasia requires further investigation.
Purpose of the Study:
- To determine if there is an association between pharyngeal reflux and adenoid hyperplasia in children.
- To utilize 24-hour dual-probe esophageal pH monitoring to assess reflux patterns.
- To compare reflux parameters in children with and without adenoid hyperplasia.
Main Methods:
- Prospective study involving 30 children with adenoid hyperplasia and 12 healthy controls.
- All participants underwent 24-hour dual-probe esophageal pH monitoring (distal and proximal).
- Data analysis performed using Measurement and Analysis Software of Medical Measurement System (Version: 7.2a).
Main Results:
- The frequency of pharyngeal reflux was significantly higher in the adenoid hyperplasia group (46.7%) compared to controls (8.3%).
- Gastroesophageal reflux (GER) was also more frequent in the study group (64.5%) than in controls (25%).
- No significant correlation was found between pharyngeal reflux, GER, and the mean adenoid nasopharyngeal ratio (ANR).
Conclusions:
- Children with adenoid hyperplasia exhibit a greater incidence of pharyngeal reflux compared to healthy children.
- These findings suggest that pharyngeal reflux may be a significant factor in the etiology of adenoid hyperplasia.
- Further research is warranted to elucidate the precise mechanisms linking pharyngeal reflux and adenoid hypertrophy.
Objectives:
The purpose of the study is to investigate whether there is any association between pharyngeal reflux and adenoid hyperplasia by using 24-h esophageal pH monitoring with a dual probe in children.
Methods:
The study group consisted of 30 children with adenoid hyperplasia, and the control group consisted of 12 healthy children, studied prospectively. All children underwent 24-h esophageal pH monitoring with a dual probe (distal and proximal esophageal pH monitoring). The results were evaluated by the Measurement and Analysis Software of Medical Measurement System program (Version: 7.2a).
Results:
In the study group, the frequency of pharyngeal reflux was 46.7% and the gastroesophageal reflux (GER) was 64.5%, while, in the control group, they were 8.3% and 25%, respectively. There was a significant difference between study and control groups for frequencies of pharyngeal reflux and GER. Mean adenoid nasopharyngeal ratio (ANR) was 0.78+/-0.11 in children with adenoid hyperplasia. There was not a significant difference between positive pharyngeal reflux, positive GER and mean ANR (p>0.05).
Conclusions:
Children with adenoid hyperplasia had higher frequency of pharyngeal reflux than children at the same age healthy group. These results supported that pharyngeal reflux may play an important role in the etiology of adenoid hyperplasia.
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