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Incidence of Type 1 diabetes in children in Cáceres, Spain, during 1988-1999

R E Lora-Gómez1, F M Morales-Pérez, F J Arroyo-Díez

  • 1Pediatric Endocrinology Section, Department of Pediatrics, Complejo Hospitalario de Cáceres, Cáceres, Spain. ricardolora1@yahoo.es

Diabetes Research and Clinical Practice
|July 12, 2005
PubMed

Insights

The incidence of Type 1 diabetes in children under 14 in Cáceres is moderately high, with higher rates observed in older children and during autumn/winter. This finding challenges the north-to-south decrease hypothesis in Europe.

Area of Science:

  • Pediatrics
  • Epidemiology
  • Endocrinology

Background:

  • Type 1 diabetes (T1D) is a significant global health concern in pediatric populations.
  • Understanding regional incidence variations is crucial for public health planning and resource allocation.

Purpose of the Study:

  • To determine the incidence of T1D in children under 14 years of age in Cáceres, Spain.
  • To analyze T1D incidence trends based on age, sex, and season of diagnosis.

Main Methods:

  • Retrospective data collection of T1D cases with onset before 14 years between 1988 and 1999.
  • Utilized pediatric registries, diabetic association records, and blood-glucose meter data.
  • Employed the capture-recapture method for comprehensive case ascertainment, achieving 99.2% completeness.

Main Results:

  • Identified 137 new T1D cases over 12 years.
  • The average annual incidence was 16.8 per 100,000 children.
  • Incidence rates increased with age, peaking in the 10-13 year group, and showed a seasonal pattern with a peak in autumn and winter.

Conclusions:

  • Cáceres exhibits a moderately high T1D incidence in children, comparable to other developed Spanish regions and Northern European countries.
  • The findings do not support a hypothesis of decreasing T1D incidence from north to south across Europe.
  • The study highlights the importance of considering age and seasonal factors in T1D epidemiology.
Abstract

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