Related Experiment Video
Updated: Aug 17, 2026

A Detailed Protocol for Physiological Parameters Acquisition and Analysis in Neurosurgical Critical Patients
Published on: October 17, 2017
Basic principles of cerebrospinal fluid metabolism and intracranial pressure homeostasis
Chang Yong Han1, Douglas D Backous
1Department of Otolaryngology/Head and Neck Surgery, Maryknoll General Hospital, 12 4-Ga Daechung Joong-Ku, Pusan, Korea.
Abstract:
Significant progress has been made in understanding the production,circulation, and absorption of CSF. In part because of autoregulation, rapid changes in arterial pressure produce parallel but significantly dampened changes in CSF pressure. Chronic arterial hypertension rarely affects ICP,but changes in venous pressure are transmitted directly into the CSF, taking precedence over arterial effects. An understanding of basic CSF physiology,particularly in relation to ICP homeostasis, is important for surgeons treating intracranial hypertension, low ICP pressure, and spontaneous,traumatic, or iatrogenic CSF leakages. The principles discussed in this article are valuable to remember when planning surgical procedures in the head and neck, both to prevent and to treat potential complications related to increased or decreased CSF pressure.
More Related Videos
Related Concept Videos
Cerebrospinal Fluid
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain.
Increased Intracranial Pressure ll: Pathophysiology
Increased Intracranial Pressure l: Introduction
Cerebral Edema l: Introduction
Cerebral Edema ll: Pathophysiology
Fluid Movement Between Compartments

