Neuronal migration on laminin in vitro
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Updated: Aug 13, 2026
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An Organotypic Slice Assay for High-Resolution Time-Lapse Imaging of Neuronal Migration in the Postnatal Brain
Published on: December 11, 2010
1Department of Neurosurgery, University of Cincinnati School of Medicine, OH 45267-0515.
Brain Research. Developmental Brain Research
|March 20, 1992
Abstract:
Chick sympathetic (E-9) or telencephalic (E-7) neurons were cultured at low density on poly-DL-ornithine (PORN), poly-L-lysine (POLS), laminin or laminin-covered PORN or POLS and monitored with time-lapse videomicroscopy. Neurons migrated on laminin, or laminin-covered PORN or POLS, but not on PORN or POLS alone. Neuronal migration did not involve interactions with other cells indicating that neurons are capable of independent migration when exposed to a laminin substrate.
