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Transfusion-transmitted infections: existing and emerging pathogens
1Department of Immunohaematology and Blood Transfusion, Government Medical College and Hospital, Sector 32, Chandigarh, India. gpsluthra@hotmail.com
Journal of Postgraduate Medicine
|July 12, 2005
Summary
Transfusion-transmitted infections (TTIs) are a reduced risk globally, but bacterial, parasitic, and emerging infections remain a concern, especially in developing nations like India.
Area of Science:
- Transfusion Medicine
- Infectious Diseases
- Public Health
Background:
- The risk of transfusion-transmitted infections (TTIs) has significantly decreased due to advanced screening methods.
- However, bacterial, parasitic, and emerging infections transmitted via blood transfusion continue to pose a threat.
Purpose of the Study:
- To review the current landscape of transfusion-transmitted infections.
- To highlight emerging pathogens and assess the TTI risk in developing countries, specifically India.
Main Methods:
- A comprehensive MEDLINE search was conducted.
- Relevant transfusion medicine literature was reviewed and data extracted.
Main Results:
- Developed countries have largely mitigated TTI risks through stringent donor criteria and sensitive detection methods.
- Developing countries, such as India, still face considerable risks from transfusion-transmitted pathogens.
Conclusions:
- While TTIs are reduced, vigilance against bacterial, parasitic, and novel infectious agents is crucial.
- Addressing the persistent TTI threat in developing nations requires ongoing attention and improved strategies.