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Related Experiment Videos

AIDS with acute cerebral infarct: a case report.

Lin-Hui Wu1, Wei-Hung Chen, Li-Ming Lien

  • 1Department of Neurology and Infectious Disease, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.

Acta Neurologica Taiwanica
|July 13, 2005
PubMed
Summary

This case study highlights a young man with acquired immunodeficiency syndrome (AIDS) who experienced both acute and old cerebral infarcts. The findings suggest a potential link between AIDS and stroke in younger individuals, a condition possibly underdiagnosed in Taiwan.

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Immunology

Background:

  • Acquired immunodeficiency syndrome (AIDS) is a chronic condition affecting the immune system.
  • Cerebrovascular events, such as stroke, can occur in individuals with compromised immune systems.

Observation:

  • A 38-year-old male presented with acute left hemiplegia.
  • Brain MRI confirmed an acute cerebral infarct in the right subcortical region and an old infarct.
  • Diagnostic tests revealed human immunodeficiency virus (HIV) infection with a low CD4+ T-cell count (149 cells/mm3).

Findings:

  • The patient exhibited prothrombotic factors, including decreased Protein S and elevated anticardiolipin antibodies.
  • The clinical presentation and diagnostic findings were consistent with AIDS-related cerebral infarcts.

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  • This represents a potentially novel case of stroke in an HIV-positive young adult in Taiwan.

    • Implications:

    • The findings suggest a possible association between AIDS and stroke in younger populations.
    • This case underscores the importance of considering HIV/AIDS in young patients presenting with cerebrovascular events.
    • Further research is warranted to explore the mechanisms linking HIV/AIDS and stroke, particularly in under-recognized populations.