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[Patent foramen ovale and stroke].
J M Meier1, A Delabays, G Girod
1Service de cardiologie, Centre hospitalier universitaire vaudois, Lausanne, Suisse. Jean-Marc.Meier@chuv.hospvd.ch
Archives Des Maladies Du Coeur Et Des Vaisseaux
|July 13, 2005
Summary
Patent foramen ovale (PFO) affects a quarter of adults and is linked to cryptogenic strokes in over 40% of patients under 60. Early identification and multidisciplinary treatment of PFO can lead to promising long-term outcomes.
Area of Science:
- Cardiology
- Neurology
- Medical Diagnostics
Context:
- Patent foramen ovale (PFO) is a common cardiac anomaly, present in approximately 25% of the adult population.
- PFO is frequently observed in younger patients (<60 years) experiencing cryptogenic ischemic stroke, occurring in over 40% of this demographic.
- Interatrial septal aneurysm can coexist with PFO, though less common.
Purpose:
- To identify clinical and echocardiographic parameters for stratifying risk in patients with cryptogenic stroke.
- To evaluate the efficacy of a multidisciplinary approach in managing patients with PFO and cryptogenic stroke.
- To assess the long-term results of correcting cardiac anomalies in selected high-risk patients.
Summary:
- Clinical and echocardiographic findings can identify patients at high risk for recurrent cryptogenic stroke, even with aspirin therapy.
- A significant association exists between PFO and cryptogenic ischemic stroke in patients under 60.
- A multidisciplinary strategy involving correction of the cardiac anomaly shows promising long-term results for selected patients.
Impact:
- Improved risk stratification for cryptogenic stroke recurrence.
- Enhanced understanding of the role of PFO in younger stroke patients.
- Evidence supporting interventional closure of PFO in specific high-risk populations.
- Potential for improved long-term prognosis and reduced stroke recurrence through targeted treatment.