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Updated: Aug 17, 2026

Measuring Bacterial Load and Immune Responses in Mice Infected with Listeria monocytogenes
Published on: August 9, 2011
A novel role for the LisRK two-component regulatory system in listerial osmotolerance
Abstract:
Understanding how pathogenic bacteria sense and respond to environmental signals, including those involved in triggering virulence gene expression, is a fundamental biological goal. It is now known that the two-component regulatory system LisRK has a novel role in osmosensing and osmoregulation in the intracellular foodborne pathogen Listeria monocytogenes. Furthermore, htrA, a gene linked to osmotolerance and virulence potential in L. monocytogenes, is now known to be under the transcriptional control of LisRK.
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