[Frequency of the anomalous coronary origin in the Chinese population with coronary artery stenosis]
Feng Zhang1, Jun-bo Ge, Ju-ying Qian
1Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai 200032, China.
Insights
Anomalous coronary origin occurs in 0.78% of Chinese patients, with the right coronary artery being most common. These anomalies do not increase the risk of coronary atherosclerotic stenosis.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Congenital anomalies of the coronary arteries are variations in their origin or course.
- Understanding the prevalence and clinical significance of these anomalies is crucial for patient management.
Purpose of the Study:
- To determine the frequency of anomalous coronary origin using coronary angiography in the Chinese population.
- To investigate the relationship between anomalous coronary origin and the development of coronary atherosclerotic stenosis.
Main Methods:
- Retrospective review of diagnostic coronary angiograms from January 2001 to June 2004.
- Identification and assessment of patients with anomalous coronary artery origins.
- Recording of significant stenosis in anomalous or non-anomalous coronary arteries.
Main Results:
- 32 out of 4094 patients (0.78%) exhibited anomalous coronary origins.
- The anomalous right coronary artery was most frequent (65.6%), followed by the anomalous left circumflex artery (15.6%).
- Significant stenosis was observed in only 15.6% of anomalous arteries, significantly lower than the overall coronary artery lesion incidence (34.3%).
Conclusions:
- The incidence of anomalous coronary origin in the Chinese population is comparable to other ethnic groups.
- An anomalous right coronary artery is the most common anomaly identified.
- Anomalous coronary arteries do not appear to confer an increased risk for developing coronary atherosclerotic stenosis.
Objective:
To estimate the frequency of anomalous coronary origin with angiography in the Chinese population and evaluate the correlation between anomalous coronary origin and development of coronary atherosclerotic stenosis.
Methods:
All of the patients who underwent diagnostic coronary angiography from January 2001 to June 2004 were retrospectively reviewed. Those with anomalous origin of the coronary arteries were selected for further assessment and any significant stenosis in one or more coronary arteries or in a major branch was recorded.
Results:
Among the 4094 patients, 32 (0.78%) had anomalies of coronary origin. Right coronary artery was the most common anomalous vessel, being involved in 21 (65.6%) patients. It originated from the left sinus of Valsalva in 19 and from the non-coronary aortic sinus in 2 patients. Anomalous left circumflex artery was the second most common anomaly, being seen in 5 (15.6%) patients. Anomalous left main coronary artery from the right sinus of Valsalva and anomalous left coronary artery from pulmonary artery were seen in 3 patients, respectively. Significant lesions in the anomalous arteries were seen in only 5 (15.6%) patients, much less than the overall incidence of coronary artery lesion in patients with coronary anomalies in this series (34.3%). Moreover, no patient was found that the anomalous vessel was the only one involved in coronary atherosclerotic stenosis.
Conclusions:
The incidence of anomalous coronary origin in Chinese population is almost as same as in other races and an anomalous right coronary artery is the most common anomaly. The anomalous coronary artery does not appear to be of any increased risk for development of coronary atherosclerotic stenosis.
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