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Published on: February 10, 2011
Device-related infections in children
Samir S Shah1, Michael J Smith, Theoklis E Zaoutis
1Division of Infectious Diseases, The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA. shahs@email.chop.edu
Insights
Device-related infections require specific management, including device removal for certain bloodstream infections and all shunt infections. New antimicrobial-impregnated devices show promise in reducing infection rates.
Area of Science:
- Infectious Diseases
- Medical Device Technology
- Pediatric Healthcare
Background:
- Device-related infections pose significant challenges in healthcare settings.
- Central venous catheters and ventriculoperitoneal shunts are common medical devices associated with infection risks.
- Certain microorganisms, like Staphylococcus aureus and Candida spp., indicate potential disseminated infections in pediatric patients.
Purpose of the Study:
- To summarize current management strategies for device-related infections.
- To highlight the importance of organism identification in diagnosing disseminated infections.
- To explore future research directions and emerging technologies for infection prevention.
Main Methods:
- Review of management protocols for device-related infections.
- Analysis of clinical significance of specific organism isolation.
- Evaluation of emerging technologies like antimicrobial-impregnated devices.
Main Results:
- Device removal is crucial for specific catheter-related bloodstream infections and all ventriculoperitoneal shunt infections.
- Isolation of Staphylococcus aureus or Candida spp. in children with central catheters warrants investigation for disseminated infection.
- Antimicrobial-impregnated central venous catheters and ventricular shunts demonstrate potential for reducing device-related infections.
Conclusions:
- Effective management of device-related infections often necessitates device removal.
- Prompt identification of specific pathogens is critical for diagnosing and managing potential disseminated infections.
- Advancements in medical device technology, particularly antimicrobial impregnation, offer promising strategies for future infection control.
Abstract:
Management of device-related infections includes device removal for some catheter-related bloodstream infections and all ventriculoperitoneal shunt-related infections. The isolation of certain organisms (eg, Staphylococcus aureus, Candida spp) in children with central catheters should prompt consideration of disseminated infection. Future research may determine the impact of increasing catheter use in non-intensive care hospital settings and in home care. New technologies, such as antimicrobial-impregnated central venous catheters and ventricular shunts, show promise in reducing the infection rates of these devices.
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