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Updated: Aug 17, 2026

Intra-Cardiac Injection of Human Prostate Cancer Cells to Create a Bone Metastasis Xenograft Mouse Model
Published on: November 4, 2022
Metastatic testicular seminoma to the prostate
Scott B Farnham1, Stephen E Mason, Joseph A Smith
1Department of Urologic Surgery, Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2765, USA. scott.farnham@vanderbilt.edu
Abstract:
Prostatic involvement by seminoma is extremely rare. Four case studies have reported primary seminoma of the prostate. Three previous reports have been published of primary testicular seminoma with metastasis to the prostate. We report a fourth case with 10 years of follow-up and describe the initial management with orchiectomy and platinum-based chemotherapy, local pelvic tumor recurrence, subsequent salvage chemotherapy, and finally cystoprostatectomy with ileal neobladder. The patient was disease free at last follow-up 4 years after surgery.
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