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Updated: Aug 17, 2026
10:50
Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding
Published on: September 15, 2010
Physiologically stable vanadium(IV) porphyrins as a new class of anti-HIV agents
Suk-Yu Wong1, Raymond Wai-Yin Sun, Nancy P-Y Chung
1Department of Chemistry and Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, SAR, China.
Chemical Communications (Cambridge, England)
|July 13, 2005
Abstract:
The water soluble oxovanadium(IV) tetraarylporphyrin has demonstrated excellent solution stability against glutathione reduction and high potency (5 microM, 97% inhibition) in inhibiting HIV-1 replication in Hut/CCR5 cells.
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