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In vitro antimicrobial activity of Fill Canal, Sealapex, Mineral Trioxide Aggregate, Portland cement and EndoRez

C R Sipert1, R P Hussne, C K Nishiyama

  • 1Endodontic Division, Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo, Bauru, Brazil.

International Endodontic Journal
|July 14, 2005
PubMed
Abstract

Insights

Fill Canal and Sealapex showed broad antimicrobial activity against tested microorganisms. Mineral Trioxide Aggregate (MTA) and Portland cement were also effective, while EndoRez lacked antimicrobial properties in this in vitro study.

Area of Science:

  • Microbiology
  • Biomaterials Science
  • Endodontics

Background:

  • Dental materials play a crucial role in endodontic treatment.
  • Assessing the antimicrobial properties of root canal sealers is essential for preventing persistent infections.

Purpose of the Study:

  • To evaluate the in vitro antimicrobial activity of Fill Canal, Sealapex, Mineral Trioxide Aggregate (MTA), Portland cement, and EndoRez.
  • To compare the efficacy of these materials against a range of oral microorganisms.

Main Methods:

  • The diffusion method on Müller-Hinton agar was utilized.
  • Seven different microbial species, including bacteria and Candida albicans, were tested.
  • Zones of inhibition were measured after incubation to assess antimicrobial effects.

Main Results:

  • Fill Canal and Sealapex exhibited antimicrobial activity against all tested microbial strains.
  • MTA and Portland cement inhibited most strains, with the exception of E. coli.
  • EndoRez demonstrated no significant antimicrobial activity.

Conclusions:

  • Fill Canal, Sealapex, MTA, and Portland cement possess in vitro antimicrobial properties relevant to endodontic applications.
  • EndoRez was found to be ineffective as an antimicrobial agent in this study.
  • These findings highlight the varying antimicrobial spectra of common endodontic materials.

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