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Updated: Aug 10, 2026
08:51
Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice
Published on: May 10, 2019
Using the derived auditory brain stem response to estimate traveling wave velocity
Ear and Hearing
|April 1, 1992
Summary
Traveling wave velocity (TWV) estimation shows potential for evaluating Meniere
Area of Science:
- Audiology
- Neuroscience
- Ophthalmology
Background:
- Meniere's disease diagnosis can be challenging.
- Objective measures are needed for early detection and monitoring.
- Auditory evoked potentials offer potential diagnostic insights.
Purpose of the Study:
- To assess the utility of traveling wave velocity (TWV) estimation in young adults.
- To determine if TWV estimation can serve as a tool for evaluating Meniere's disease.
- To compare TWV measurements with established diagnostic methods.
Main Methods:
- Utilized a derived auditory brain stem response (ABR) procedure.
- Employed high-intensity acoustic masking during testing.
- Evaluated 18 healthy young adult participants.
Main Results:
- Average TWVs were comparable to those from psychophysical measures and electrocochleography.
- Some subjects showed faster-than-expected TWVs due to undermasking.
- Subject intolerance to masking impacted data acquisition in certain cases.
Conclusions:
- TWV estimation using ABR shows promise as a potential diagnostic aid for Meniere's disease.
- Further refinement of the high-intensity masking technique is warranted.
- Addressing subject tolerance is crucial for reliable TWV measurements in clinical settings.
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