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Updated: Aug 17, 2026

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
Published on: May 11, 2014
Narrow band imaging in Barrett's esophagus
1Division of Gastroenterology and Hepatology, University of Kansas School of Medicine, Kansas City, MO, USA. psharma@kumc.edu
Abstract:
Barrett's esophagus is the premalignant lesion for esophageal and esophagogastric junction adenocarcinoma. Progression of Barrett's esophagus to dysplasia and cancer can occur, thus requiring endoscopy with random biopsy examinations. Currently, the diagnosis of metaplastic and dysplastic mucosa within the esophagus requires endoscopy with biopsy examination of abnormal-appearing tissue. The presence of intestinal metaplasia and dysplasia within the esophagus often is patchy, and our current practices of performing standard endoscopy with random biopsy examinations are inaccurate. Narrow band imaging is among several tools used in the esophagus to improve detection of Barrett's esophagus and associated dysplasia. Current studies show that these techniques are promising, although the results still are preliminary.
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