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Updated: Aug 12, 2026

Analysis of Chromosome Segregation, Histone Acetylation, and Spindle Morphology in Horse Oocytes
Published on: May 11, 2017
[Impact of the maternal age variable on ovular harvesting, fertilization and segmentation in a program of assisted
P Di Castro Stringher1, J Hernández Vazquez, A Kably Ambe
1Laboratorio de Gametos y Clínica de Reproducción Asistida, Instituto Nacional de Perinatología, México, D.F.
Abstract:
The increased maternal age was found as responsible for the ovaric biological failure, that in turn, becomes an altered hormonal response, and a reduction in the amount of susceptible ovocytes, susceptible for capture; this diminution in the amount of ovocytes, and not an intrinsic alteration in its quality is at the moment the biological translation of ovarian aging. Therefore, maternal age variable, with its ovarian and endometrial repercussion, becomes the variable with the greatest impact in Assisted Reproduction programs. The variable age is statistically independent from other variables as procedure indication, sterility type, used ovarian stimulation. The patients age should be considered as a very important prognostic factor, when proposing the methods os Assisted Reproduction, independently of the greater risk of gestation problems.
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