Related Experiment Video
Updated: Sep 14, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
Vulvar destruction by malignant lymphoma
1Anatomic Pathologic Division, INCOR, Hospital das Clínicas, University of São Paulo School of Medicine, Brazil.
Abstract:
Two cases of vulvar and perineal destruction by malignant lymphoma are described. The first case was of an untreated 4-year-long vulvar destruction due to a kappa-positive lymphoplasmacytic lymphoma that ultimately resulted in the death of the patient. The second patient had involvement of the vulva and perineum by an angiocentric small and large mixed-cell lymphoma. Aggressive chemotherapy induced regression and healing of the lesions in the second case. Delayed diagnosis and inappropriate management of lymphomas in the vulva may lead to widely destructive disease of the lower female genital tract.
Related Concept Videos
Abnormal Proliferation
Cancers Originate from Somatic Mutations in a Single Cell
Loss of Tumor Suppressor Gene Functions
When the tumor suppressor genes develop mutations or are lost, cells start growing out of control, leading to cancer. However, a single functional copy of the tumor suppressor gene is enough for the cells to maintain their normal functions and cell...
Cancer-Critical Genes II: Tumor Suppressor Genes
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Loss of Tumor Suppressor Gene Functions
When the tumor suppressor genes develop mutations or are lost, cells start growing out of control, leading to cancer. However, a single functional copy of the tumor suppressor gene is enough for the cells to maintain their normal functions and cell...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

