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Published on: February 11, 2017
Apical hypertrophic cardiomyopathy: a case of slow flow in lad and malign ventricular arrhythmia
Emre Aksakal1, Oktay Yapici, Mustafa Yazici
1Department of Cardiology, Ondokuz Mayis University, Medical Faculty, Samsun, Turkey.
Insights
This case study highlights a rare instance of slow coronary arterial flow in a 71-year-old male with apical hypertrophic cardiomyopathy. The patient experienced chest pain and sudden cardiac arrest, underscoring the potential severity of this condition.
Area of Science:
- Cardiology
- Vascular Medicine
- Genetics
Background:
- The coronary slow flow phenomenon (CSF) is an angiographic finding of delayed distal vessel opacification without significant epicardial coronary artery disease.
- CSF is often associated with acute coronary syndromes, and histopathology reveals fibromuscular hyperplasia and myofibrillar hypertrophy.
- Apical hypertrophic cardiomyopathy (AHC) is a progressive form of hypertrophic cardiomyopathy, typically asymptomatic until advanced stages, and rare in Western populations.
Observation:
- A 71-year-old male presented with chest pain and sudden cardiac arrest.
- The patient was diagnosed with apical hypertrophic cardiomyopathy.
- The presentation was attributed to slow coronary arterial flow.
Findings:
- This case demonstrates a rare association between apical hypertrophic cardiomyopathy and the coronary slow flow phenomenon.
- The patient experienced life-threatening ventricular arrhythmia secondary to the cardiac condition.
Implications:
- This case underscores the importance of considering CSF in patients with AHC presenting with ischemic symptoms or arrhythmias.
- Early diagnosis and management of AHC and associated CSF may be crucial for preventing adverse cardiovascular events.
- Further research into the pathophysiology linking AHC and CSF is warranted to improve patient outcomes.
Abstract:
The coronary slow flow phenomenon is an angiographic finding characterized by delayed distal vessel opacification in the absence of epicardial coronary artery disease. Patients often present with acute coronary syndrome. Histopathologic studies have revealed the existence of fibromuscular hyperplasia and myofibrilar hypertrophy. Apical hypertrophic cardiomyopathy is a benign progressive form of hypertrophic cardiomyopathy, that is rarely observed in western communities. It remains commonly asymptomatic until advanced ages. Syncope, arrhythmia or sudden death may be the first symptom. We report a case of slow coronary arterial flow in a 71-year-old male patient with apical hypertrophic cardiomyopathy who experienced chest pain and sudden cardiac arrest due to ventricular arrhythmia.
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